Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

591
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
591

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder.

Annals of clinical and translational neurology·2026
Same author

Desired clinic characteristics and unmet support needs for adults with multiple sclerosis: A cross-sectional survey.

Multiple sclerosis journal - experimental, translational and clinical·2026
Same author

The Impact of Hormonal Stages of Life in Women With Multiple Sclerosis: A Survey Study of the Menstrual Cycle.

Archives of physical medicine and rehabilitation·2026
Same author

Cognitive Screening and Neuropsychological Evaluation in Children and Young Adults With Childhood-Onset Systemic Lupus Erythematosus: A Survey of Rheumatologists.

ACR open rheumatology·2026
Same author

Do MRI-negative relapses really exist? - No.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Reconstructing multi-scale tissue spatial architecture from single-cell RNA-seq with REMAP.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Aug 13, 2025

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
10:50

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo

Published on: March 26, 2019

7.8K

Challenging Cases in Neuroimmunology.

Anna A Shah1, Andrew B Wolf1, Anthony Declusin1

  • 1Department of Neurology, Rocky Mountain MS Center, University of Colorado School of Medicine, Aurora, Colorado.

Seminars in Neurology
|January 23, 2023
PubMed
Summary

Neuroimmunology is advancing rapidly, presenting diagnostic and treatment challenges. This review highlights six complex cases, offering insights into managing conditions like multiple sclerosis and antibody-mediated disorders.

More Related Videos

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis EAE Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
08:38

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis EAE Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge

Published on: April 9, 2012

20.5K
Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.4K

Related Experiment Videos

Last Updated: Aug 13, 2025

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
10:50

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo

Published on: March 26, 2019

7.8K
Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis EAE Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
08:38

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis EAE Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge

Published on: April 9, 2012

20.5K
Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.4K

Area of Science:

  • Neuroimmunology
  • Neurology
  • Autoimmune Disorders

Background:

  • Neuroimmunology is a rapidly evolving field.
  • Dozens of novel antibody-mediated disorders have been identified recently.
  • Diagnosing and treating these conditions presents significant clinical challenges.

Purpose of the Study:

  • To discuss challenging neuroimmunological cases.
  • To highlight nuances in diagnosis and management.
  • To provide insights for clinicians managing complex neurological conditions.

Main Methods:

  • Case study review from an institutional setting.
  • Discussion of diagnostic criteria and management strategies.
  • Focus on six informative and complex patient cases.

Main Results:

  • Detailed examination of tumefactive multiple sclerosis.
  • Exploration of antibody-mediated encephalitis.
  • Analysis of antiphospholipid antibody syndrome, neuromyelitis optica, and MOG-IgG disease.

Conclusions:

  • Challenging cases underscore the complexity of neuroimmunological disorders.
  • Effective management requires a deep understanding of diagnostic nuances.
  • Clinical experience sharing is crucial for advancing patient care in neuroimmunology.