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Fatality due to acute hydrofluoric acid exposure
K M Chan1, W P Svancarek, M Creer
1Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110.
Journal of Toxicology. Clinical Toxicology
|January 1, 1987
Summary
Severe hydrofluoric acid exposure can be fatal, causing rapid metabolic disturbances. Prompt recognition and treatment are crucial for managing these severe burns.
Area of Science:
- Toxicology
- Emergency Medicine
- Dermatology
Background:
- Hydrofluoric acid (HF) burns are common industrial and household injuries.
- While typically manageable, massive exposure poses a significant risk.
Observation:
- Two cases of fatal, extensive hydrofluoric acid exposure are presented.
- Patients experienced acute systemic metabolic acidosis, hypocalcemia, and hypomagnesemia.
Findings:
- Death occurred within three hours post-exposure in both cases.
- Systemic toxicity, including electrolyte derangements, was the primary cause of fatality.
Implications:
- Highlights the critical need for immediate, specialized treatment protocols for severe HF burns.
- Emphasizes the importance of preventative measures and rapid diagnostic recognition to improve patient outcomes.