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Septic arthritis and subsequent fatal septic shock caused by Pasteurella multocida in Vietnam

Nguyen Thi Hong Nhi1, Pham Dang Hai2

  • 1College of Health Sciences, VinUniversity, Viet Nam.

New Microbes and New Infections
|January 24, 2023
PubMed

Insights

A fatal septic shock case resulted from a knee joint infection caused by Pasteurella multocida, a bacteria common in dogs and cats. This highlights an uncommon but severe complication of P. multocida infections.

Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Pasteurella multocida is a common Gram-negative bacterium residing in the upper respiratory tract of animals, particularly domestic pets.
  • Infections typically manifest as localized cellulitis, with systemic complications like septic shock being rare.

Purpose of the Study:

  • To report a rare fatal case of septic shock originating from a knee joint infection by Pasteurella multocida.

Main Methods:

  • Case report detailing a patient with a natural knee joint infection.
  • Clinical assessment and microbiological identification of Pasteurella multocida.

Main Results:

  • The patient developed septic shock secondary to a Pasteurella multocida knee joint infection.
  • The infection proved fatal, underscoring the potential severity of P. multocida infections.

Conclusions:

  • Pasteurella multocida can cause severe, fatal infections, including septic shock, even from seemingly localized joint infections.
  • This case emphasizes the importance of considering P. multocida in joint infections, especially in animal handlers.
Keywords:
ALT, Alanine transaminaseAST, Aspartate aminotransferaseCRP, C-reactive proteinCirrhosisINR, International Normalized RatioPT, ProthrombinPasteurella multocidaSeptic arthritisSeptic shockVietnam

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