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Updated: Aug 13, 2025

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Published on: December 24, 2014
Meeting report of the 3rd European Biotransformation Workshop
Markus Walles1, Axel Pähler2, Emre M Isin3
1Department of Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Abstract:
Challenges, strategies and new technologies in the field of biotransformation were presented and discussed at the 3rd European Biotransformation Workshop which was held in collaboration with the DMDG on 5-6 October 2022 in Amsterdam. In this meeting report we summarise the presentations and discussions from this workshop. The topics covered are listed below:Accelerator mass spectrometry (AMS) for the support of microtracer studiesBiotransformation of the novel myeloperoxidase inhibitor AZD4831 in preclinical species and humansAMS in biotransformation studies: unusual case studiesDiscussion on new FDA draft guidance and AMSMultimodal molecular imaging and ion mobility applications in drug discovery and developmentMetabolites in Safety Testing considerations for large molecules.
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