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Updated: Aug 13, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
[Multiple loci account for human height]
1Biologiste, généticien et immunologiste, Président d'Aprogène (Association pour la promotion de la Génomique), 13007 Marseille, France.
Abstract:
The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant "missing heritability", and these loci appear to be functionally relevant. This work is a model for future studies on the genetic determinants of complex diseases.
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