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Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Published on: December 5, 2020

Natural Product-Based Crop Protection Compounds─Origins and Future Prospects.

Thomas C Sparks¹, Janine M Sparks², Stephen O Duke³

¹Agrilucent LLC, Morro Bay, California 93442, United States.

Journal of Agricultural and Food Chemistry

|January 24, 2023

Summary

This summary is machine-generated.

Natural products (NPs) are crucial for developing new crop protection agents, inspiring 17% of active ingredients. Bacterial NPs are increasingly important, driving innovation in insecticides and other pest management tools.

Keywords:

agrochemical discovery fungicide herbicide innovation in agrochemical discovery insecticide natural product-based crop protection compounds natural products

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Area of Science:

Agricultural Science
Natural Product Chemistry
Pest Management

Background:

Growing global population necessitates enhanced food and fiber production.
Natural products (NPs) are vital sources for discovering new crop protection active ingredients (AIs).
NPs inspire a significant portion of crop protection compounds, including synthetic equivalents.

Purpose of the Study:

To analyze the impact and trends of natural products in crop protection AI discovery.
To identify key sources and classes of natural product-inspired crop protection agents.
To highlight the continuing value of natural products in agricultural innovation.

Main Methods:

Literature and patent analysis of natural product-derived crop protection agents.
Quantification of natural product contributions to different AI classes (insecticides, herbicides).
Tracking trends in natural product research and development over time.

Main Results:

Natural products account for 17% of all crop protection AIs, with potential for 50% including NPSEs.
NPs primarily influence insecticide discovery, with less impact on herbicides.
Bacterial NPs have become the leading source of new classes of NP-inspired AIs in the last 30 years, surpassing plants.

Conclusions:

Natural products remain a critical resource for discovering novel crop protection compounds.
The trend shows increasing research and patent activity, underscoring the sustained interest in NPs.
Bacterial sources are emerging as highly valuable for next-generation pest management solutions.