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Published on: June 2, 2014
Atopic Disorders and Their Risks of Migraine: A Nationwide Population-Based Cohort Study
Ju Hee Han1, Hyun Ji Lee2, Hwa Jung Yook1
1Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Individuals with atopic disorders, such as eczema, asthma, and allergic rhinitis, face a higher risk of developing migraine. The risk increases with the number of co-occurring atopic conditions.
Area of Science:
- Neurology
- Dermatology
- Allergology
Background:
- Migraine is a prevalent neurological condition.
- A potential association between atopic disorders and migraine has been previously suggested.
- This study aimed to investigate this link within the Korean population.
Purpose of the Study:
- To examine the association between atopic disorders and the risk of developing migraine.
- To determine if the number of atopic conditions influences migraine risk.
Main Methods:
- Utilized data from the Korean National Health Insurance Service database (2009).
- Included adult patients (≥ 20 years) who underwent health screening.
- Employed Cox proportional hazards regression analyses to assess migraine risk.
Main Results:
- Atopic dermatitis, asthma, and allergic rhinitis were all significantly associated with an increased risk of migraine.
- Patients with one, two, or three atopic disorders showed progressively higher risks of migraine compared to controls.
- Adjusted hazard ratios (aHR) indicated significant associations for each condition and number of conditions.
Conclusions:
- Atopic disorders are linked to an elevated risk of migraine.
- A dose-response relationship exists, where more atopic conditions correlate with a greater migraine risk.
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