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Updated: Aug 12, 2025

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Is It Possible to Eliminate Postoperative Shunt Infections?: Results of a Modified Hydrocephalus Clinical Research
Mohammad Elbaroody1, Adham Ezz1, Amr Helmy Eldessouky1
1Department of Neurosurgery, Cairo University, Kasr Alainy Faculty of Medicine, Cairo, Egypt.
Background:
Postoperative shunt infection is a nightmare in neurosurgical practice with additional morbidity and mortality. A lot of protocols have contributed to the reduction of ventriculoperitoneal shunt (VPS) infections but not eradication. The aim of the study was to evaluate the rigid application of a modified Hydrocephalus Clinical Research Network (HCRN) protocol in the prevention of postoperative shunt infection.
Methods:
We retrospectively evaluated children with congenital hydrocephalus who underwent VPS insertion, and in whom the protocol was applied from June 2019 to January 2020. Follow-up ranged from 11 to 24 months.
Results:
Thirty-seven procedures were performed including 35 primary shunt insertions and two revision surgeries. The median age was 5 months (range, 1-30 months), and 25 patients were males. The most common cause for VPS placement was congenital hydrocephalus without identifiable cause in 28 cases (80%). The endoscope-assisted technique was used in the insertion of the proximal end in six cases (17%). The mean follow-up was 19.4 months (11-24 months). The rate of shunt infection was 0% till the last follow-up.
Conclusion:
The preliminary results showed an effective method for the prevention of postoperative shunt infections using the modified protocol. These initial findings need to be validated in a large prospective study before widespread application can be recommended.
Insights
A modified Hydrocephalus Clinical Research Network (HCRN) protocol effectively prevented ventriculoperitoneal shunt (VPS) infections in pediatric patients, achieving a 0% infection rate in a retrospective study. Further validation is needed for broader recommendations.
Area of Science:
- Neurosurgery
- Pediatric Surgery
- Infectious Disease Prevention
Background:
- Postoperative shunt infection poses significant risks in neurosurgery.
- Existing protocols have reduced, but not eliminated, ventriculoperitoneal shunt (VPS) infections.
- Preventing VPS infections remains a critical challenge in managing hydrocephalus.
Purpose of the Study:
- To evaluate the efficacy of a modified Hydrocephalus Clinical Research Network (HCRN) protocol in preventing postoperative shunt infections.
- To assess the impact of rigid protocol adherence on infection rates in pediatric patients undergoing VPS insertion.
- To determine the feasibility of a zero-infection rate using the modified protocol.
Main Methods:
- Retrospective evaluation of pediatric patients with congenital hydrocephalus who underwent VPS insertion.
- Application of a modified HCRN protocol from June 2019 to January 2020.
- Follow-up duration ranged from 11 to 24 months.
Main Results:
- 37 procedures were performed on 37 children (median age 5 months; 25 males).
- Congenital hydrocephalus was the primary indication for VPS placement in 80% of cases.
- A 0% shunt infection rate was observed during the mean follow-up period of 19.4 months.
Conclusions:
- The modified HCRN protocol demonstrated effectiveness in preventing postoperative shunt infections.
- Preliminary findings suggest this protocol is a promising strategy for reducing shunt infection rates.
- Larger prospective studies are recommended to validate these results before widespread adoption.

