Neuromuscular disorder in rabbit--a pathological study

Rabbits affected by a neuromuscular disorder have been observed by light and electron microscopy. The presynaptic portion of the neuromuscular junction showed many changes such as depletion or reduction in synaptic vesicle population, degenerative changes in mitochondria. Intra-muscular axons showed few changes such as disorientation and ramification of neurofilaments. The muscle fibres showed some degenerated fibres and increased collagen around the muscle fibres. Intramuscular blood capillaries also showed proliferation of endothelial cells.