Related Experiment Video
Updated: Jul 14, 2026

A Step by Step Protocol for Subretinal Surgery in Rabbits
Published on: September 13, 2016
27-GAUGE PARS PLANA/PLICATA VITRECTOMY FOR PEDIATRIC VITREORETINAL SURGERY
Cindy Ung1, Yoshihiro Yonekawa2, Mina M Chung3
1South Coast Retina Center, Long Beach, California.
This study found that 27-gauge vitrectomy is a safe and feasible surgical option for pediatric patients with various vitreoretinopathies. The procedure demonstrated good anatomical success and improved visual acuity in young patients.
Area of Science:
- Ophthalmology
- Pediatric Surgery
Background:
- Pediatric vitreoretinopathy presents unique surgical challenges.
- Minimally invasive techniques are increasingly explored for pediatric eye surgery.
Purpose of the Study:
- To evaluate the feasibility and safety of 27-gauge vitrectomy in pediatric patients.
- To assess surgical outcomes, including complications and visual acuity, in this population.
Main Methods:
- An international, multicenter, retrospective case series involving 47 pediatric patients (56 eyes) aged 17 years or younger.
- Patients underwent 27-gauge vitrectomy for conditions such as retinopathy of prematurity, Terson's syndrome, and traumatic macular holes.
- Data on intraoperative events, postoperative complications, and visual acuity were collected and analyzed.
Main Results:
- No intraoperative complications or postoperative endophthalmitis were reported.
- Instrument bending occurred in 1.8% of cases; 7.1% required conversion to a larger gauge, and 5.3% developed postoperative hypotony.
- Mean visual acuity improved significantly (P=0.01), with 96.4% achieving anatomical success after one surgery.
Conclusions:
- Twenty-seven-gauge vitrectomy is a safe and feasible ultra-small gauge surgical option for selected pediatric vitreoretinopathies.
- Further research is needed to fully understand the indications and long-term outcomes of this technique in pediatric ophthalmology.
More Related Videos
11:20Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
11:06Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care
Published on: November 11, 2022