[Value of hemodynamic parameters in determining kidney transplant function (animal experiments and clinical...

From the demonstrated results is to be concluded: 1. The haemodynamic and functional inquiries on animal experimental and clinical kidney grafts suppose that the tubules and the renal vascular system are comparably affected by the damaging influences of the different preservation methods. 2. This pathogenetic relationship is apparently maintained also in the regeneration phase; i.e. the tubular restitution is connected with an improvement of the blood-supply of the organ. 3. The discrepancy between the morphologic and functional findings of storage and perfusion preserved kidneys shows that the efficiency of the graft is not only defined by definitive structural changes, but also by other factors, such as metabolites, enzymatic and humoral influences, changes of the local blood composition, regional conditions of blood-supply, and so on. 4. Due to the significant relation between restrictions of the renal blood-supply and the renal function after transplantation haemodynamic parameters are suitable for the judgment of renal preservation methods and for the prognostic estimation of renal grafts.