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Risk of Neurological Decline in Patients With Temporal Lobe Brain Masses.
Jared Sweeney1, Melanie Bondoc2, Sruti Bandlamuri2
1Department of Neurosurgery, Albany Medical Center, Albany, NY, U.S.A. sweenej2@amc.edu.
Anticancer Research
|January 25, 2023
Summary
Neurological decline in temporal lobe mass lesions is predicted by radiographic transtentorial herniation. Findings like midline shift greater than 5 mm also indicate increased risk, aiding clinical management.
Area of Science:
- Neurosurgery
- Neurology
- Radiology
Background:
- Temporal lobe mass lesions can lead to neurological decline.
- Identifying predictive factors for decline is crucial for patient management.
Purpose of the Study:
- To identify clinical and radiographic findings associated with neurological decline in patients with temporal lobe mass lesions.
Main Methods:
- Retrospective cohort study of 71 adult patients with temporal lobe masses.
- Neurological decline defined as Glasgow Coma Scale decrease of ≥2 or new anisocoria.
- Linear regression analysis to identify predictive findings.
Main Results:
- Incidence of neurological decline was 6% (4/71 patients).
- Radiographic transtentorial herniation was a significant predictor of neurological decline (p=0.03).
- Midline shift >5 mm and transtentorial herniation were more prevalent in patients with decline.
Conclusions:
- Radiographic transtentorial herniation and midline shift >5 mm may indicate increased neurological decline risk.
- These findings can aid neurosurgeons and other specialists in managing temporal lobe mass lesions.
