Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

153
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
153
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

596
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
596
Panic Disorder01:27

Panic Disorder

163
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
163
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

193
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
193
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

237
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
237
Sex-linked Disorders01:43

Sex-linked Disorders

102.6K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
102.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A narrative review of energy expenditure and substrate oxidation during menopause.

Climacteric : the journal of the International Menopause Society·2026
Same author

Editorial: Exercise and menopause: benefits, challenges and the transition to optimal management.

Frontiers in sports and active living·2026
Same author

The dose-response effects of nitrate-rich beetroot ingestion on cardiovascular and endothelial function: a randomised controlled trial.

Food & function·2026
Same author

2025 Update to the Female Athlete Triad Coalition Consensus Statement Part 2: Clinical Guidelines for Screening, Diagnosis, Treatment, and Return to Play for Adolescents and Adults.

Sports medicine (Auckland, N.Z.)·2025
Same author

2025 Update to the Female Athlete Triad Coalition Consensus Statement Part 1: State of the Science and Introduction of a New Adolescent Model.

Sports medicine (Auckland, N.Z.)·2025
Same author

Effectiveness of Interventions to Improve Cardiovascular Perturbations in Women with Exercise-Associated Amenorrhea: A Systematic Review.

Women's health reports (New Rochelle, N.Y.)·2025
Same journal

Classifying Psychedelic-Related Complications.

Current topics in behavioral neurosciences·2026
Same journal

Psychedelic-Related Psychosis: From Model Psychosis to Psychotherapy.

Current topics in behavioral neurosciences·2026
Same journal

Managing Psychological Challenges in the Subacute ("Afterglow") Window of Psychedelic Drug Effects.

Current topics in behavioral neurosciences·2025
Same journal

Flashbacks, Hallucinogen Persisting Perception Disorder (HPPD), and Reactivations Following the Use of Classic Psychedelics: Classification and Therapeutic Management.

Current topics in behavioral neurosciences·2025
Same journal

Correction to: Psychedelic Drug Checking: Analytical and Strategic Challenges in Harm Reduction for Classic Psychedelics.

Current topics in behavioral neurosciences·2025
Same journal

Ontologically Challenging Psychedelic Experiences: Considerations for Managing Associated Distress.

Current topics in behavioral neurosciences·2025
See all related articles

Related Experiment Video

Updated: Aug 12, 2025

Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways
10:44

Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways

Published on: December 9, 2013

12.1K

Sex Differences in Dementia.

Eef Hogervorst1, Sophie Temple2, Emma O'Donnell2

  • 1National Centre for Sports and Exercise Medicine (NCSEM), School of Sports Exercise and Health Sciences (SSEHS), Loughborough University, Loughborough, UK. e.hogervorst@lboro.ac.uk.

Current Topics in Behavioral Neurosciences
|January 25, 2023
PubMed
Summary
This summary is machine-generated.

Women face a higher risk of Alzheimer's disease (AD) due to sex-specific factors like declining sex hormones post-menopause and differing cardiovascular disease (CVD) risks. Lifestyle and hormonal changes significantly impact dementia susceptibility in women.

Keywords:
AgeCardiovascularDementiaRisk/protective factorsSexSex steroids

More Related Videos

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
06:23

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

Published on: October 13, 2016

32.6K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.1K

Related Experiment Videos

Last Updated: Aug 12, 2025

Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways
10:44

Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways

Published on: December 9, 2013

12.1K
The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
06:23

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

Published on: October 13, 2016

32.6K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.1K

Area of Science:

  • Neuroscience
  • Endocrinology
  • Public Health

Background:

  • Women exhibit a higher prevalence of Alzheimer's disease (AD), the most common dementia.
  • This review examines sex-driven differences in dementia, distinguishing biological sex from social gender constructs.

Approach:

  • A narrative review was conducted to explore dementia characteristics, risk factors, and sex-specific differences.
  • Key areas examined include hormonal changes, cardiovascular disease (CVD) prevalence, and lifestyle factors influencing dementia risk.

Key Points:

  • Declining sex steroid hormones after menopause in women may increase susceptibility to dementia and CVD.
  • Menopause occurring at an earlier age is associated with increased risk for both conditions.
  • Cardiovascular disease shares risk factors with dementia, and men's earlier mortality from CVD means fewer survive to develop AD.

Conclusions:

  • Sex-specific hormonal changes and differing risk factor profiles contribute to dementia prevalence disparities.
  • Further research is needed to investigate the interplay between hormonal decline, lifestyle factors, and dementia risk in women.
  • Combined hormone therapy and lifestyle interventions in midlife may offer preventative strategies for dementia and CVD.