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A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

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Hypoglycemic hemineglect a stroke mimic.

Adrian Rodriguez-Hernandez¹, Denis Babici¹, Maryellen Campbell¹

¹Department of Neurology, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, United States.

Eneurologicalsci

|January 26, 2023

Summary

Severe hypoglycemia can mimic a stroke, causing temporary hemineglect. This case highlights the importance of checking glucose levels in stroke alerts to avoid misdiagnosis.

Keywords:

Hemineglect Hypoglycemia Stroke mimic

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Area of Science:

Neurology
Endocrinology
Internal Medicine

Background:

Acute hypoglycemia, a complication of diabetes mellitus, can present with neurological deficits.
Prompt recognition and management are crucial to prevent severe outcomes.

Observation:

A 60-year-old male with diabetes presented with stroke-like symptoms, including left-sided hemineglect.
Initial brain imaging showed decreased perfusion in the right cortical area, raising stroke concerns.

Findings:

Despite initial stroke-like findings, urgent magnetic resonance imaging (MRI) excluded acute ischemic stroke.
The patient's symptoms resolved completely with close glucose monitoring and management in the Intensive Care Unit.

Implications:

This case underscores that severe hypoglycemia can manifest as transient hemineglect syndrome, a presentation not previously well-documented.
Clinicians should consider blood glucose levels as a critical differential diagnosis in patients presenting with acute neurological deficits, especially those with diabetes.
Timely glucose level assessment in emergency settings can prevent misdiagnosis and ensure appropriate treatment, avoiding unnecessary interventions for stroke.