Related Experiment Video
Updated: Aug 12, 2025

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
Published on: May 14, 2014
Core Mechanisms in Action Control: Binding and Retrieval
Andrea Kiesel1, Lisa R Fournier2, Carina G Giesen3
1University of Freiburg, DE.
Abstract:
This special collection focuses on action control and its two postulated core processes, namely feature binding and retrieval. Action control is an important topic as humans interact with their environment by means of goal-directed behavior, i.e. by means of actions. Cognitive processes were developed and shaped to enhance preparation, execution, and regulation of action. Therefore, it is the current consensus that cognition serves action. To date, research on human action control is comprised mainly of an abundance of paradigm-specific results and models. To gain a better understanding of action control, an integrative framework was proposed (the BRAC framework - for Binding and Retrieval in Action Control, Frings et al., 2020) that can explain a wide range of findings across different experimental paradigms by assuming two core processes as key functions in action control: feature binding and feature retrieval. In this special collection, 20 articles present and discuss different types of sequential paradigms in terms of this integrative account. This editorial explains the major assumptions of the BRAC framework and provides an integrative overview of the articles that are included in this special collection.
Related Concept Videos
Cooperative Binding of Transcription Regulators
Conserved Binding Sites
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
Assembly of Signaling Complexes
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Ligand Binding and Linkage
Targets for Drug Action: Overview
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
Internal Receptors

