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Evaluation of the aorta in infants with simple or complex coarctation of the aorta using CT angiography

Hui-Jun Xiao1, A-Lai Zhan1, Qing-Wen Huang1

  • 1Department of Radiology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.

Frontiers in Cardiovascular Medicine
|January 26, 2023
PubMed

Insights

Infants with coarctation of the aorta (CoA) face risks of ascending aortic dilatation. The degree of coarctation is a key predictor, identifiable through computed tomography angiography (CTA).

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Medical Imaging

Background:

  • Coarctation of the aorta (CoA) is a congenital heart defect.
  • Ascending aortic dilatation is a potential complication in infants with CoA.
  • Computed tomography angiography (CTA) is a valuable tool for cardiac imaging.

Purpose of the Study:

  • To assess aortic dilatation in infants with coarctation of the aorta (CoA).
  • To identify factors related to aortic dilatation in infants with CoA.
  • To evaluate the utility of CTA in identifying aortic dilatation risk in infants with CoA.

Main Methods:

  • Retrospective analysis of clinical data from 52 infant patients with CoA diagnosed by CTA.
  • Measurement of aortic diameters at six levels, standardized as Z scores.
  • Logistic regression analysis to determine predictors of ascending aortic dilatation.

Main Results:

  • Ascending aortic dilatation was observed in infants with both simple and complex CoA.
  • Infants with complex CoA showed more aortic arch hypoplasia compared to simple CoA.
  • Increased degree of coarctation (CDR value) was an independent predictor of ascending aortic dilatation.

Conclusions:

  • Infants with CoA, both simple and complex, are at risk for ascending aortic dilatation.
  • The degree of coarctation is a significant factor influencing ascending aortic dilatation.
  • CTA can effectively identify the risk of aortic dilatation in infants with CoA.
Abstract

Keywords:
CTACoAaortic dilatationdiagnosisinfant

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