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Updated: Aug 12, 2025

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Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST - RE1-silencing transcription

Pavel Veverka1,2, Tomáš Brom1, Tomáš Janovič1

  • 1LifeB, FGP - NCBR, Faculty of Science, Masaryk University, Kamenice 753/5, Brno 625 00, Czech Republic.

Computational and Structural Biotechnology Journal
|January 26, 2023
PubMed

Keywords:
CD, circular dichroismCoIP, coimmunoprecipitationDLS, dynamic light scatteringDifferentiationEMEM, electron microscopyElectron microscopyIDRs, intrinsically disordered regionsNRSE, neuron-restrictive silencer elementNRSFNRSF, neuron-restrictive silencer factorNeuron-restrictive silencer factorNeuronalPCNA, proliferating cell nuclear antigenRD1/2, repressor domain 1/2RE1, repressor element-1RE1-silencing transcription factorRESTREST, RE1-silencing transcription factorREST-FL, full-length RESTREST-N62REST-N62, splicing isoform of REST, also known as REST4 or REST4-S3REST4ZF, zinc fingeraa, amino acid(s)bp, base pair(s)kDa, kilodaltons

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