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The relationship between H2FPEF score and contrast induced nephropathy in patients with ST elevation myocardial

Ufuk Sadik Ceylan1, Ersin Yıldırım2

  • 1Istanbul Dr. Siyami Ersek Education and Research Hospital, University of Health Sciences, Department of Cardiology, Istanbul, Turkey.

Journal of Cardiovascular and Thoracic Research
|January 26, 2023
PubMed

Insights

The H2FPEF score can predict Contrast Induced Nephropathy (CIN) in patients with ST-elevation myocardial infarction (STEMI). This score offers a simple method to estimate CIN risk following primary coronary angioplasty.

Area of Science:

  • Cardiology
  • Nephrology
  • Medical Diagnostics

Background:

  • Contrast Induced Nephropathy (CIN) is a complication following procedures using contrast dye.
  • ST-elevation myocardial infarction (STEMI) patients undergoing primary coronary angioplasty are at risk for CIN.
  • Predictive tools for CIN are crucial for risk stratification and management in STEMI patients.

Purpose of the Study:

  • To investigate the association between the H2FPEF score and the development of CIN.
  • To evaluate the predictive value of the H2FPEF score for CIN in STEMI patients undergoing primary coronary angioplasty.

Main Methods:

  • Retrospective analysis of 355 STEMI patients who underwent primary coronary angioplasty.
  • Patients were categorized into CIN (+) and CIN (-) groups.
  • H2FPEF score was calculated upon admission and compared between groups.

Main Results:

  • The H2FPEF score was significantly higher in the CIN (+) group (2.00±1.60) compared to the CIN (-) group (1.25±1.26).
  • H2FPEF score (OR: 1.25) and mean age (OR: 1.03) were independently associated with CIN development.
  • 63 patients (17.7%) developed CIN.

Conclusions:

  • The H2FPEF score is an independent predictor of CIN in acute STEMI patients.
  • The H2FPEF score is easily calculable and can aid in estimating CIN risk.
  • Utilizing the H2FPEF score may improve patient management and outcomes in STEMI.

Keywords:
Contrast Induced NephropathyH2FPEF ScoreMyocardial InfarctionPercutaneous Coronary Intervention

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