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Updated: Aug 12, 2025

Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy
Published on: May 1, 2012
Integrative visualization of the molecular structure of a cellular microdomain
David S Goodsell1,2,3,4, Keren Lasker1
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
Abstract:
An integrative approach to visualization is used to create a visual snapshot of the structural biology of the polar microdomain of Caulobacter crescentus. The visualization is based on the current state of molecular and cellular knowledge of the microdomain and its cellular context. The collaborative process of researching and executing the visualization has identified aspects that are well determined and areas that require further study. The visualization is useful for dissemination, education, and outreach, and the study lays the groundwork for future 3D modeling and simulation of this well-studied example of a cellular condensate.
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