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A Review of Midface Aging.
Shoaib Ugradar1, Jane S Kim2, Guy Massry3,4
1The Jules Stein Eye Institute, University of California, Los Angeles, California, U.S.A.
Ophthalmic Plastic and Reconstructive Surgery
|January 26, 2023
Summary
Facial aging involves midface anatomical changes, including bone structure alterations and fat pad migration. Soft tissue changes are primary drivers of aging appearance, necessitating further research for quantification.
Area of Science:
- Anatomy
- Aging
- Facial Plastic Surgery
Background:
- The midface anatomy is intricate, with aging causing significant involutional changes.
- Existing studies on midface aging present variable scientific quality and conflicting outcomes.
Approach:
- A comprehensive PubMed literature search was conducted.
- The review focused on studies detailing midface anatomy and age-related involutional alterations.
Key Points:
- Midface aging involves decreased maxillary and pyriform angles, altered orbital floor position.
- Inferior migration of midface fat compartments exacerbates grooves (palpebromalar, nasojugal).
- Buccal fat pad volume changes contribute significantly to the aged facial appearance.
Conclusions:
- Midface aging is predominantly characterized by soft tissue alterations.
- Further rigorous studies are needed to quantify these changes and their impact on overall aging manifestations.

