Related Experiment Video
Updated: Aug 12, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Construction of Alkylidene Fluorene Scaffolds Using Pd-Catalyzed Direct Arene/Alkene Coupling Strategy
Hidenori Matsuyama1, Xuan Zhang2, Masahiro Terada1
1Department of Chemistry, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan.
Abstract:
A versatile synthetic method for the construction of alkylidene fluorenes and their heteroarene derivatives has been developed successfully by means of a Pd(II)-catalyzed direct C-H/C-H coupling of o-alkenyl biaryls. Use of the Pd(OAc)2 catalyst under aerobic oxidation conditions gives rise to the corresponding alkylidene fluorenes having various functional groups and diversely fused polycyclic systems. The resulting products can serve as versatile synthetic building blocks for the construction of structurally diverse polycyclic arenes and heteroarenes.
More Related Videos
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
09:35Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Related Concept Videos
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry
Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.
Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene
Cycloaddition Reactions: Overview