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Updated: Aug 11, 2026

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Published on: April 24, 2018
Using freshwater snail Biomphalaria glabrata (Say, 1818) as a biological model for ecotoxicology studies: a
Gabriel Souza-Silva1, Clessius Ribeiro de Souza2, Cíntia Aparecida de Jesus Pereira3
1Postgraduate Program in Medicines and Pharmaceutical Assistance, Faculty of Pharmacy, Federal University of Minas Gerais-Belo Horizonte/MG, Belo Horizonte, Brazil. silva_gs@yahoo.com.
Abstract:
Over time, a growing increase in human pollutants in the aquatic environment has been observed. The global presence of residues in water bodies reinforces the need to develop improved methods to detect them and evaluate their ecotoxicological effects in aquatic environments. Thus, this study aimed to present the main assays using Biomphalaria glabrata as a biological model for ecotoxicological studies. We performed a systematic literature review with data published up to June 2022 on the Web of Science, SCOPUS, Science Direct, PubMed, and SciELO databases. Thirty studies were selected for this review after screening. Biomphalaria glabrata has been studied as an ecotoxicological model for different substances through toxicity, embryotoxicity, cytotoxicity, genotoxicity, and bioaccumulation assays. Studies evaluating the impact of B. glabrata exposure to several substances have reported effects on their offspring, as well as toxicity and behavioral and reproductive effects. This review presents various assays using B. glabrata as a biological model for ecotoxicological studies. The use of a representative species of ecosystems from tropical regions is a necessary tool for tropical environmental monitoring. It was observed that the freshwater snail B. glabrata was effective for the evaluation of the ecotoxicity of several types of chemical substances, but further studies are needed to standardize the model.
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