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Delayed onset sympathetic ophthalmia.

K A McClellan1, F A Billson, M Filipic

  • 1Sydney Eye Hospital, Woolloomooloo, NSW.

The Medical Journal of Australia
|November 2, 1987
PubMed
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Sympathetic ophthalmia, a rare condition, can occur decades after eye injury or surgery. This study highlights delayed onset and risks associated with further procedures on injured eyes.

Area of Science:

  • Ophthalmology
  • Immunology

Background:

  • Sympathetic ophthalmia is a rare, bilateral granulomatous panuveitis.
  • It typically occurs after penetrating ocular trauma or intraocular surgery.

Observation:

  • Three cases of delayed sympathetic ophthalmia are presented.
  • Onset occurred up to 62 years post-injury (shot-gun pellet) or surgery.
  • Two cases involved subsequent surgeries on previously injured eyes.

Findings:

  • Bilateral granulomatous panuveitis developed within a week in one case and seven years later in another.
  • Delayed onset suggests long-term immune system changes post-ocular injury.

Implications:

  • The risk of elective surgery in eyes predisposed to sympathetic ophthalmia requires careful consideration.

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  • Patient counseling regarding long-term risks and monitoring is crucial.