Reliability of fast-spin echo T2-weighted three-dimensional sequences to predict endoscopic third

Etienne Lefevre1,2, Yohan Caudron3,4, Kevin Beccaria5,6

  • 1Department of Neurosurgery - Pitié-Salpêtrière Hospital, Paris, France.

Insights

3D fast-spin echo T2-weighted sequences accurately assess endoscopic third ventriculocisternostomy (ETV) patency in children. This reproducible tool demonstrates excellent interrater reliability, making it suitable for daily clinical practice.

Area of Science:

  • Pediatric Neurosurgery
  • Neuroradiology
  • Medical Imaging

Background:

  • Assessing the patency of endoscopic third ventriculocisternostomy (ETV) in pediatric patients presents clinical and radiological challenges.
  • Reliable methods are needed to evaluate ETV function post-surgery.

Purpose of the Study:

  • To evaluate the accuracy and interrater reliability of 3D fast-spin echo (FSE) T2-weighted sequences for determining ETV patency in children.

Main Methods:

  • A retrospective study included children who underwent ETV surgery, comparing those with dysfunction to a matched control group without dysfunction.
  • Three experienced physicians assessed ETV patency using the flow void sign on 3D FSE T2-weighted sequences.
  • Interrater reliability was calculated using Fleiss' kappa.

Main Results:

  • The study analyzed 19 children with ETV dysfunction and 12 matched controls.
  • Sensitivity ranged from 0.79 to 0.89, and specificity was 1 for all raters.
  • Fleiss' kappa was 0.871 (p < 0.001), indicating excellent interrater reliability for assessing ETV patency.

Conclusions:

  • 3D FSE T2-weighted sequences are a simple, reproducible tool for assessing ETV patency in pediatric patients.
  • The sequence offers high interrater reliability and is accessible for outpatient use.
  • This imaging technique can be widely adopted in routine clinical practice.
Abstract