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Subnuclear associations of the v-myb oncogene product and actin are dependent on ionic strength during nuclear
1Department of Pathology, School of Medicine, University of California, Los Angeles 90024.
Molecular and Cellular Biology
|September 1, 1987
Abstract:
The method used to isolate nuclei has a direct effect on the subnuclear association of the v-myb product, p48v-myb, and nuclear actin. Analysis of nuclei subjected to various isolation procedures showed that disruption of native nuclear structure during hypotonic treatment resulted in dissociation of p48v-myb from the nuclear matrix.