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Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Dipesh Karki1, Roshani Gurung2, Prasanna Nepali3

  • 1Department of Medicine, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.

JNMA; Journal of the Nepal Medical Association
|January 27, 2023
PubMed

Insights

The prevalence of elevated D-dimer in hospitalized COVID-19 patients was 47.22%. This finding for D-dimer levels in COVID-19 patients was lower than in other similar studies.

Area of Science:

  • Medical Research
  • Infectious Diseases
  • Hematology

Background:

  • COVID-19 is associated with abnormal inflammatory biomarkers, including elevated D-dimer.
  • Elevated D-dimer levels in COVID-19 patients correlate with increased mortality risk.

Purpose of the Study:

  • To determine the prevalence of elevated D-dimer in COVID-19 patients admitted to a tertiary care center.

Main Methods:

  • A descriptive cross-sectional study was conducted between January and June 2021.
  • Data on D-dimer levels and demographics were collected from 180 hospitalized COVID-19 patients.
  • Convenience sampling and calculation of point estimates with 95% Confidence Intervals were employed.

Main Results:

  • Out of 180 COVID-19 patients, 85 (47.22%) exhibited elevated D-dimer levels.
  • The 95% Confidence Interval for the prevalence was 39.93% to 54.51%.

Conclusions:

  • The prevalence of raised D-dimer among admitted COVID-19 patients in this tertiary care center was 47.22%.
  • This prevalence was observed to be lower compared to findings in similar studies.
Abstract

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