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Lauromacrogol foam injection under ultrasonic guidance for pediatric lip venous malformations
Keyao Li1, Yanling Jiang1, Zhu Wei1
1Department of Dermatology, Hunan Children's Hospital, Changsha, 410007, China.
Insights
Lauromacrogol foam sclerotherapy guided by ultrasound is a safe and effective treatment for children with lip venous malformations (VM). This minimally invasive procedure achieved a high success rate with minimal side effects in a recent study.
Area of Science:
- Vascular Surgery
- Pediatric Surgery
- Minimally Invasive Procedures
Background:
- Venous malformations (VM) are common congenital vascular anomalies.
- Lip VM can cause significant cosmetic and functional issues in children.
- Current treatment options for pediatric lip VM have limitations.
Purpose of the Study:
- To assess the efficacy and safety of lauromacrogol foam sclerotherapy for treating lip venous malformations in pediatric patients.
- To determine the complication rate associated with this procedure in children.
Main Methods:
- Retrospective study of 52 children (6 months to 17 years) with lip VM treated between July 2018 and December 2020.
- Lauromacrogol foam injection under ultrasound guidance to target VM nests.
- Pre-operative assessment included MRI, ultrasound, and blood tests; follow-up involved clinical and imaging evaluation.
Main Results:
- An average of 4 treatment sessions per child resulted in a total effective rate of 90.38%.
- Minor complications included pain (4 cases), fever (4 cases), infection (2 cases), and ulceration (1 case).
- No serious adverse events like cardiopulmonary complications were reported.
Conclusions:
- Ultrasound-guided lauromacrogol foam sclerotherapy is a highly effective treatment for pediatric lip venous malformations.
- The procedure demonstrates a favorable safety profile in children, with manageable side effects.
- This technique offers a promising minimally invasive option for managing lip VM in pediatric populations.
Objective:
To evaluate the efficacy and safety of lauromacrogol foam sclerotherapy in the treatment of children with lip venous malformation.
Methods:
Fifty-two children (27 males and 25 females) aged from 6 months to 17 years with lip VM who underwent lauromacrogol foam injection with ultrasonic guidance from July 2018 to December 2020 in our hospital were retrospectively recruited for this study. All the children were examined by MRI, ultrasound, blood routine and coagulation before operation. We were guided by ultrasound to locate the blood flow area (nests), injecting lauromacrogol foam to fill the venous malformation. The follow-up time was 14.31 ± 5.96 (6-24) months. Follow-up items include clinical manifestations, imaging data, efficacy and complications.
Results:
This group of children was treated 3-5 times, an average of 4 times/case. The total effective rate was 90.38%. Pain in 4 cases, fever in 4 cases, infection in 2 cases, ulcer in 1 case. There were no serious complications such as cardiopulmonary accident.
Conclusion:
Ultrasound guiding foam sclerotherapy with lauromacrogol is effective and safe for children with lip venous malformation.
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