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Updated: Aug 12, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine-derived CDK2 inhibitors as anticancer agents: Design, synthesis &

Biruk Sintayehu Fanta1, Laychiluh Mekonnen1, Sunita K C Basnet1

  • 1Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, South Australia 5000, Australia.

Bioorganic & Medicinal Chemistry
|January 27, 2023
PubMed

Keywords:
2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidineAntiproliferative activityBioisosteric replacementCDK2CDK2 inhibitorCDKI-73

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