Cemento-Ossifying Fibroma With Cerebral Involvement

Area of Science:

• Oral and Maxillofacial Pathology
• Oncology

Background:

• Cemento-ossifying fibroma (COF) is a rare fibro-osseous neoplasm.
• It predominantly affects individuals in their third and fourth decades of life.
• COF represents a distinct variant among ossifying fibromas, alongside juvenile trabecular and psammomatoid types.

Purpose of the Study:

• To describe the key characteristics of Cemento-ossifying fibroma.
• To highlight its histological features and growth potential.

Main Methods:

• Histological examination of COF.
• Review of clinical presentation and demographic data.

Main Results:

• COF is characterized by high cellularity and a fibrous stroma with variable calcification.
• The tumor demonstrates significant growth potential despite a benign histological classification.

Conclusions:

• Cemento-ossifying fibroma is a distinct entity within fibro-osseous lesions.
• Understanding its cellularity and growth potential is crucial for management.