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The Effect of the Application of Thyme Essential Oil on Microbial Load During Meat Drying
Published on: March 14, 2018
Characterization of thymol derivatives from Eupatorium fortunei Turcz. aerial parts
Hieu Nguyen-Ngoc1, Bui Thi Thu Trang2, Do Thi Hoai Thu3
1Faculty of Pharmacy, PHENIKAA University, Hanoi, Vietnam.
Abstract:
From the aerial parts of Eupatorium fortunei, four thymol derivatives (1-4) were isolated and structurally elucidated by NMR and mass spectroscopic methods. Of which, a new dimeric thymol derivative (1) was characterized and its absolute configuration was established by electronic circular dichroism quantum method. In addition, the 1D and 2D NMR as well as HR-ESI mass spectral data of 2 were provided for the first time. Compounds 2-4 were evaluated for their inhibitory activity against α-glucosidase and acetylcholinesterase enzymes. All tested compounds showed weak inhibition at the concentration range of 1-256 μg/mL in both enzymatic assays.
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