Nutritional support in allogeneic hematopoietic stem cell transplantation Asian perspective

Area of Science:

• Hematology
• Transplantation Medicine
• Nutritional Science

Background:

• Allogeneic hematopoietic stem cell transplantation (allo-HSCT) improves outcomes for hematological diseases but carries risks.
• Malnutrition is a significant concern for allo-HSCT patients, impacting recovery.
• Current nutritional support practices in allo-HSCT lack robust evidence and standardized strategies.

Purpose of the Study:

• To review current knowledge on nutritional support in allo-HSCT.
• To identify challenges and gaps in nutritional management for allo-HSCT recipients.
• To emphasize the need for improved strategies and training, with an Asian perspective.

Main Methods:

• Literature review of studies in non-HSCT and allo-HSCT settings.
• Analysis of existing guidelines and clinical practices.
• Focus on data relevant to the Asia-Pacific region.

Main Results:

• Lack of large-scale randomized prospective studies hinders evidence-based nutritional strategies in allo-HSCT.
• Physician knowledge gaps and limited access to registered dietitians (RDs) are barriers in some Asia-Pacific countries.
• Existing guidelines for nutritional support may not be fully implemented.

Conclusions:

• There is a critical need for well-established, evidence-based nutritional support strategies for allo-HSCT.
• Enhanced training for RDs in HSCT nutritional management is essential.
• Addressing regional barriers, particularly in the Asia-Pacific, is crucial for optimizing patient outcomes.