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Calcium Carbonate (Tums)-Associated Hypercalcemic Crisis.

Hanish Jain1, Sindhubarathi Murali2, Garima Singh3

  • 1Internal Medicine, Upstate University Hospital, Syracuse, USA.

Cureus
|January 30, 2023
PubMed
Summary

Excessive intake of calcium carbonate, a common antacid, can lead to hypercalcemic crisis, a serious condition causing kidney failure. Physicians should recognize this risk and educate patients on safe usage of over-the-counter medications.

Keywords:
acute hypercalcemiacalcium alkali syndromecalcium carbonategastroesophageal reflux disorder (gerd)hypercalcemic crisismilk alkali syndromeover-the-counter

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Area of Science:

  • Nephrology
  • Endocrinology
  • Internal Medicine

Background:

  • Hypercalcemic crisis is a severe medical emergency with potentially fatal outcomes, including renal failure and altered mental status.
  • Common causes include malignancy, primary hyperparathyroidism, granulomatous diseases, and certain medications like thiazide diuretics, lithium, and teriparatide.

Observation:

  • This report details a case of hypercalcemic crisis precipitated by excessive ingestion of calcium carbonate, a widely available over-the-counter antacid.
  • The patient presented with symptoms indicative of severe hypercalcemia, necessitating urgent medical intervention.

Findings:

  • Excessive calcium carbonate consumption can lead to a life-threatening hypercalcemic crisis.
  • This adverse effect is often overlooked as calcium carbonate is a common over-the-counter medication for acid reflux.

Implications:

  • Healthcare providers must be vigilant in identifying calcium carbonate overdose as a cause of hypercalcemic crisis.
  • Patient education regarding the risks associated with excessive intake of over-the-counter calcium supplements is crucial for preventing adverse events.