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Prognostic value of Siglec-15 expression in patients with solid tumors: A meta-analysis
Kui-Ying Jiang1, Li-Li Qi1,2, Xin-Bo Liu3
1Department of Orthopedic Oncology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Frontiers in Oncology
|January 30, 2023
Summary
Siglec-15 expression is linked to varied survival outcomes in solid tumors, correlating with poorer overall survival but better disease-specific survival. Further research is needed to fully understand its prognostic value in cancer patients.
Area of Science:
- Oncology
- Immunology
- Biomarkers
Background:
- Siglec-15 is expressed in various cancers, but its prognostic role is debated.
- Understanding Siglec-15's impact is crucial for cancer patient outcomes.
Conclusions:
- Siglec-15 expression is significantly associated with diverse outcomes in human solid tumors.
- Further studies are required to definitively establish the prognostic significance of Siglec-15 in cancer.
