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Osteosarcoma Around a Ceramic-on-Ceramic Total Hip Arthroplasty
Jordan J Levett1, Robert E Turcotte2, Sungmi Jung3
1Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.
Arthroplasty Today
|January 30, 2023
Summary
Sarcomas, rare cancers near total hip arthroplasty (THA) implants, present diagnostic challenges. Early consideration of osteosarcoma is crucial for periprosthetic masses, especially after ceramic-on-ceramic THA.
Area of Science:
- Orthopedic Oncology
- Arthroplasty Research
- Medical Device Safety
Background:
- Sarcomas developing at total hip arthroplasty (THA) sites are rare but serious complications.
- Literature review and case report focus on osteosarcoma around hip implants.
Observation:
- A novel case of osteosarcoma occurring around a ceramic-on-ceramic THA is presented.
- Analysis included 13 studies, detailing sarcomas in proximity to hip prostheses.
- The average time from initial THA to sarcoma diagnosis was 9.3 years.
Findings:
- This is the first reported instance of sarcoma associated with a ceramic-on-ceramic hip implant.
- Outcomes for patients with sarcomas around THA were consistently poor across reviewed literature.
- Osteosarcoma is a critical differential diagnosis for periprosthetic masses after THA.
Implications:
- Highlights the importance of considering rare malignancies in patients with hip implants experiencing new symptoms.
- Underscores the need for vigilance in diagnosing periprosthetic masses, even with advanced implant materials.
- Suggests potential long-term risks associated with THA, necessitating further investigation into sarcoma etiology.

