Related Experiment Video
Updated: Aug 12, 2025

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Reinke Edema: Factors that Interfere with Vocal Recovery after Surgery.
José Luiz Lima Neto1, Antônio Rodrigues Bueno da Fonseca1, Elaine Lara Mendes Tavares1
1Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, Universidade Estadual Paulista Julio de Mesquita Filho, Unesp Botucatu, São Paulo, Brazil.
Vocal symptoms often persist after Reinke edema surgery, even with vocal rest. Chronic smoking, maintained post-surgery, is a key factor contributing to persistent dysphonia and laryngeal changes.
Area of Science:
- Otolaryngology
- Laryngology
- Speech Pathology
Background:
- Reinke edema surgery frequently results in persistent dysphonia and lower pitch.
- Chronic smoking is a primary cause, but other factors may contribute to these outcomes.
Purpose of the Study:
- To evaluate laryngeal microsurgery outcomes for Reinke edema.
- To assess results following a standardized postoperative guidance protocol.
Main Methods:
- Retrospective study of 30 Reinke edema patients (3 male, 27 female).
- Analysis of pre- and postoperative (4-6 months) data including smoking, vocal symptoms, videolaryngostroboscopy, voice therapy, and vocal evaluations.
- Histopathological analysis of laryngeal tissue.
Main Results:
- 100% of patients were smokers; 80% continued smoking post-surgery.
- 43% reported complete symptom improvement, 40% partial, and 17% no change.
- Low adherence to voice therapy was noted. Postoperative findings included congestion, atrophy, bowed vocal folds, and subepithelial edema.
Conclusions:
- Persistent vocal symptoms and laryngeal alterations are common after Reinke edema microsurgery.
- These symptoms are linked to smoking-induced laryngeal mucosal changes, exacerbated by continued smoking.
- Even with vocal rest and reflux management, outcomes can be affected by smoking habits.
Related Concept Videos
Tonsillitis II: Management
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Endotracheal Intubation II: Nursing Management
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
Larynx
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...

