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A case of hoarseness of voice following COVID-19 infection

Ruby Joseph1, Kavitha Venkatnarayan2, Ashitha Nanaiah3

  • 1Department of Pulmonary Medicine, St. John's National Academy of Health Sciences, Bengaluru. drrubylilavati@gmail.com.

Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
|January 30, 2023
PubMed

Insights

Mucormycosis, a deadly fungal infection, can occur after COVID-19 and steroid treatment. This case highlights unusual mediastinal mucormycosis, emphasizing early diagnosis and treatment for better outcomes.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Pulmonology

Background:

  • Mucormycosis is a severe angio-invasive fungal infection with high mortality.
  • COVID-19 infection and associated steroid therapy are emerging risk factors.
  • Typical mucormycosis presentations involve rhino-orbito-cerebral, pulmonary, and other sites.

Observation:

  • A patient recovering from moderate COVID-19 pneumonia presented with an unusual manifestation of mucormycosis.
  • The infection involved the mediastinum, a rare site for this opportunistic pathogen.
  • This case underscores the need to consider mucormycosis in post-COVID-19 patients with atypical symptoms.

Findings:

  • The patient experienced mediastinal mucormycosis, a rare but life-threatening complication.
  • Prompt diagnosis and multidisciplinary management, including antifungal therapy and surgical intervention, were crucial.
  • Successful treatment averted severe morbidity and mortality in this complex case.

Implications:

  • Highlights the expanding spectrum of mucormycosis presentations in the context of COVID-19.
  • Emphasizes the importance of heightened clinical suspicion for mucormycosis in immunocompromised patients, especially post-COVID-19.
  • Reinforces the critical role of early diagnosis, antifungal treatment, and surgical debridement in managing invasive fungal infections.

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