Reactive arthritis after Gam-COVID-Vac vaccination: A case report

Area of Science:

• Immunology
• Vaccinology
• Rheumatology

Background:

• Post-vaccination surveillance for adverse events following COVID-19 immunisation is crucial.
• Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines undergo rigorous safety and efficacy evaluations.
• Investigating adverse events provides valuable insights into vaccine safety profiles.

Observation:

• A 41-year-old male without prior health issues reported left elbow joint pain and morning stiffness.
• Symptoms appeared 20 days after receiving the initial Sputnik V vaccine dose.
• The patient had no history of underlying diseases that could explain the symptoms.

Findings:

• The clinical presentation suggested a potential link between the Sputnik V vaccination and the onset of joint discomfort.
• Diagnostic investigations were performed to understand the cause of the patient's symptoms.
• A possible diagnosis of reactive arthritis was established based on the case study.

Implications:

• This case highlights the importance of monitoring and reporting potential adverse events following SARS-CoV-2 vaccination.
• Understanding vaccine-associated joint issues can inform clinical practice and patient guidance.
• Further research may be warranted to explore the incidence and mechanisms of reactive arthritis post-vaccination.