A Novel Sampling Device for the Quantification of Primary Aromatic Amines on Surfaces

Area of Science:

• Analytical Chemistry
• Occupational Health and Safety
• Polymer Science

Background:

• Primary aromatic amines (PAAs) are hazardous, with many classified as carcinogens, mutagens, or reproductive toxins (CMR).
• Dermal exposure is a significant route for PAAs uptake.
• Accurate quantification of PAAs is crucial in the polyurethane industry, particularly in workplaces with potential for regular exposure, especially when isocyanates interfere.

Purpose of the Study:

• To develop, validate, and verify a novel sampling device for selective quantification of PAAs on work surfaces.
• To create analytical papers capable of measuring PAAs while minimizing interference from isocyanates.

Main Methods:

• Synthesis and characterization of Cell-ßALA-PEMSA analytical papers using infrared spectroscopy and thermogravimetric analysis.
• Validation through recovery tests of spiked TDA and MDA.
• Selectivity testing via wipe tests on surfaces contaminated with amines and isocyanates.
• Field testing in a Polyurethane Technical Application Department.

Main Results:

• Satisfactory recovery rates for spiked TDA and MDA on the analytical papers.
• Demonstrated excellent selectivity (nearly 100%) of Cell-ßALA-PEMSA papers for PAAs in the presence of isocyanates.
• Successful initial field tests, outperforming an established surface sampling method in detecting expected PAA contamination.
• Observed significant variability in amine recovery from different surfaces.

Conclusions:

• Cell-ßALA-PEMSA analytical papers offer a promising selective method for quantifying PAAs on surfaces in industrial settings.
• The developed method is superior to established techniques for surface sampling of PAAs in the presence of isocyanates.
• Further research is needed to address the variability in amine recovery influenced by surface properties.