Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

409
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
409
Respiratory Volumes01:15

Respiratory Volumes

1.6K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
1.6K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

314
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
314
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

254
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
254
Respiratory Capacities01:24

Respiratory Capacities

870
Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
870
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

1.7K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Collapse of Nuclear Collectivity along the N=Z Line.

Physical review letters·2026
Same author

Detailed View at Magnetic Dipole Strengths: The Case of Semimagic ^{50}Ti.

Physical review letters·2026
Same author

Deviations from the Porter-Thomas Distribution due to Nonstatistical γ Decay below the ^{150}Nd Neutron Separation Threshold.

Physical review letters·2025
Same author

Gamma Decay of the ^{154}Sm Isovector Giant Dipole Resonance: Smekal-Raman Scattering as a Novel Probe of Nuclear Ground-State Deformation.

Physical review letters·2025
Same author

A resonant sextuplet of sub-Neptunes transiting the bright star HD 110067.

Nature·2023
Same author

Laparoscopic Sleeve Gastrectomy in Adolescents: Ten-Years Follow-up.

Obesity surgery·2022

Related Experiment Video

Updated: Aug 12, 2025

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

5.7K

Prediction of exercise respiratory limitation from pulmonary function tests.

D Shlomi1, T Beck2, R Reuveny3

  • 1Adelson School of Medicine, Ariel University, Ariel, Israel; Pulmonary Clinic, Dan-Petah-Tiqwa District, Clalit Health Services - Community Division, Ramat-Gan, Israel.

Pulmonology
|January 30, 2023
PubMed
Summary

Pulmonary function tests (PFTs) at rest can predict respiratory limitations during cardiopulmonary exercise testing (CPET). Specific forced expiratory volume in 1 second (FEV1) values can rule in or out respiratory issues, potentially reducing unnecessary CPETs.

Keywords:
Breathing reserveCardiopulmonary exercise testExercise physiologyPulmonary function testRespiratory limitation

More Related Videos

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

792
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

20.6K

Related Experiment Videos

Last Updated: Aug 12, 2025

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

5.7K
Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

792
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

20.6K

Area of Science:

  • Pulmonary Medicine
  • Exercise Physiology
  • Diagnostic Testing

Background:

  • Cardiopulmonary exercise testing (CPET) is crucial for evaluating unexplained exercise intolerance.
  • Traditionally, resting pulmonary function tests (PFTs) are not used to predict respiratory limitations during CPET.

Purpose of the Study:

  • To identify specific PFT cut-off values that can predict respiratory limitations in CPET.
  • To establish criteria for ruling in or ruling out respiratory limitations before CPET.

Main Methods:

  • Patients undergoing CPET were categorized into obstructive and non-obstructive spirometry groups.
  • Groups were divided into derivation and validation cohorts (2:1 ratio).
  • Analysis focused on establishing maximal and minimal PFT cut-off values for predicting respiratory limitation.

Main Results:

  • For obstructive spirometry, FEV1 ≥ 61% predicted ruled out respiratory limitation; FEV1 ≤ 33% predicted indicated limitation.
  • For non-obstructive spirometry, FEV1 ≥ 73% predicted ruled out respiratory limitation.
  • This algorithm could potentially reduce CPETs by 47% in obstructive and 71% in non-obstructive groups.

Conclusions:

  • Resting PFTs can predict the presence or absence of respiratory limitation during CPET in certain cases.
  • This predictive capability may optimize the use of CPET.