Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aquaporins01:25

Aquaporins

4.9K
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
4.9K
Fetal Circulation01:14

Fetal Circulation

1.2K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.2K
Reabsorption and Secretion in the DCT and Collecting Duct01:26

Reabsorption and Secretion in the DCT and Collecting Duct

1.5K
The early phase of the DCT manages the reabsorption of approximately 10-15% of filtered water, 5–10% of filtered sodium, and 5–10% of filtered chloride. This process is facilitated by Na+–Cl− symporters in apical membranes and sodium-potassium pumps, as well as Cl− leakage channels in basolateral membranes. The early DCT also stands out as a site where parathyroid hormone (PTH) stimulates calcium reabsorption, depending on the body's requirements.
The distal...
1.5K
Development of Blood Vessels01:07

Development of Blood Vessels

685
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
685
Formation of Dilute Urine01:20

Formation of Dilute Urine

1.8K
The formation of dilute urine is a critical renal adaptation that maintains fluid balance, particularly during periods of high fluid intake. This process primarily involves the juxtamedullary nephrons. By adjusting the permeability of water and ions in response to physiological conditions, the kidneys can either conserve or excrete water, resulting in concentrated or dilute urine.
Filtrate Osmolarity in the PCT
Initially, as the filtrate passes through the proximal convoluted tubule (PCT), its...
1.8K
Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion01:22

Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion

71
The kidneys maintain homeostasis through filtration, reabsorption, and secretion. Tubular reabsorption and secretion are crucial in forming urine and regulating electrolytes, water balance, and waste elimination.Tubular Reabsorption and Secretion ProcessesTubular reabsorption is the process that reclaims essential substances such as electrolytes, glucose, amino acids, and water from the glomerular filtrate back into the bloodstream. This is achieved through passive and active transport...
71

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal obesity shapes associations between preeclampsia and birthweight in pregnancies exposed to low-dose aspirin.

Frontiers in physiology·2026
Same author

Effect of Sertraline on Fetoplacental Growth Parameters and Placental Transporter Gene Expression in Rats.

International journal of molecular sciences·2026
Same author

In Vitro Evaluation of the Impact of Oxygen Concentrations on Thrombomodulin Expression in a First-Trimester Trophoblast Cell Line.

Archives of medical research·2025
Same author

AQP3 in amniotic epithelial cells: A key mediator of cell survival.

Placenta·2025
Same author

Editorial: SLIMP2024.

Placenta·2025
Same author

Editorial: Maternal-fetal interface: new insight in placenta research, volume II.

Frontiers in endocrinology·2025

Related Experiment Video

Updated: Aug 12, 2025

Culturing Primary Rat Inner Medullary Collecting Duct Cells
06:11

Culturing Primary Rat Inner Medullary Collecting Duct Cells

Published on: June 21, 2013

14.9K

Aquaporins in Fetal Development.

Nora Martínez1, Alicia E Damiano2,3

  • 1Laboratorio de Biología de la Reproducción, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO)-CONICET-Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.

Advances in Experimental Medicine and Biology
|January 30, 2023
PubMed
Summary
This summary is machine-generated.

Aquaporins (AQPs) are vital for fetal growth, regulating water balance and placental development. Their dysregulation is linked to pregnancy complications, highlighting their crucial role in human gestation.

Keywords:
AquaporinsFetalPlacenta

More Related Videos

Manual Drainage of the Zebrafish Embryonic Brain Ventricles
06:17

Manual Drainage of the Zebrafish Embryonic Brain Ventricles

Published on: December 16, 2012

10.1K
Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example
14:20

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example

Published on: October 8, 2014

16.1K

Related Experiment Videos

Last Updated: Aug 12, 2025

Culturing Primary Rat Inner Medullary Collecting Duct Cells
06:11

Culturing Primary Rat Inner Medullary Collecting Duct Cells

Published on: June 21, 2013

14.9K
Manual Drainage of the Zebrafish Embryonic Brain Ventricles
06:17

Manual Drainage of the Zebrafish Embryonic Brain Ventricles

Published on: December 16, 2012

10.1K
Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example
14:20

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example

Published on: October 8, 2014

16.1K

Area of Science:

  • Reproductive biology
  • Physiology
  • Molecular biology

Background:

  • Water homeostasis is critical for fetal development, relying on placental function.
  • Numerous aquaporins (AQPs) are present in the placenta throughout pregnancy.
  • AQPs are regulated by various factors including hormones and intracellular signaling.

Purpose of the Study:

  • To review the role of aquaporins in human placental function and pregnancy.
  • To explore the involvement of AQPs in maintaining amniotic fluid volume and organ development.
  • To discuss the association between placental AQP dysregulation and gestational disorders.

Main Methods:

  • Literature review of studies on aquaporins in human placenta and fetal membranes.
  • Analysis of AQP expression and function regulation.
  • Examination of AQP involvement in cellular processes and metabolic functions.

Main Results:

  • AQPs are implicated in amniotic fluid homeostasis and placental/fetal organ development.
  • Dysregulation of placental AQPs is linked to gestational disorders.
  • Aquaglyceroporins play roles in placental energy metabolism and urea transport.

Conclusions:

  • Placental AQPs are crucial for normal pregnancy, involved in cellular events like trophoblast migration and apoptosis.
  • The presence of AQP9 in trophoblast mitochondria suggests novel roles in pregnancy.
  • Further research is needed to fully elucidate the significance of AQPs in human pregnancies.