Related Experiment Video

Updated: Aug 12, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

12.7K

Epidemiology of Primary and Recurrent Healthcare-Associated and Community-Associated Pediatric Clostridioides

Anada Silva1, Tim Du2, Kelly B Choi1

  • 1Public Health Agency of Canada, Ottawa, Canada.

Journal of the Pediatric Infectious Diseases Society
|January 31, 2023
PubMed

Insights

Clostridioides difficile infection (CDI) in children is a significant health concern. This study analyzes CDI trends in Canadian children, covering both hospital and community settings, and examines recurrent cases.

Area of Science:

  • Pediatric Infectious Diseases
  • Epidemiology
  • Microbiology

Background:

  • Clostridioides difficile infection (CDI) poses a notable morbidity risk in pediatric populations.
  • Understanding the epidemiology of CDI in children is crucial for effective public health strategies.

Purpose of the Study:

  • To investigate the epidemiological and molecular characteristics of CDI in Canadian children.
  • To analyze trends in both healthcare-associated and community-associated CDI.
  • To examine patterns of recurrent CDI in pediatric patients.

Main Methods:

  • Retrospective analysis of pediatric CDI cases across Canadian healthcare settings.
  • Epidemiological data collection on patient demographics, infection source, and recurrence.
  • Molecular typing to understand transmission patterns (details not provided in abstract).

Main Results:

  • Presents epidemiological and molecular trends of CDI in Canadian children.
  • Includes data from inpatient and outpatient settings.
  • Focuses on healthcare- and community-associated cases and recurrent infections.

Conclusions:

  • Highlights the ongoing burden of CDI in pediatric populations.
  • Provides insights into the diverse sources and patterns of pediatric CDI in Canada.
  • Informs future research and clinical management of pediatric CDI.

Keywords:
community-associated pediatric CDIhealthcare-associated pediatric CDIpediatric CDI epidemiologypediatric Clostridioides difficile infectionrecurrent ­pediatric CDI

More Related Videos

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.1K
A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection09:12

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

Published on: June 15, 2018

10.2K

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.3K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
682
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.1K
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
3.9K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
22