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Updated: Aug 12, 2025
Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
Published on: February 22, 2015
[Glioblastoma in adults]
Stephanie Schipmann-Miletic1, Sarankan Sivakanesan2, Daniel Stavne Rath2
1Nevrokirurgisk avdeling, Haukeland universitetssjukehus.
Abstract:
Glioblastoma is the most common form of primary brain cancer in adults, and the disease has a serious prognosis. Although great progress has been made in molecular characteristics, no major breakthroughs in treatment have been achieved for many years. In this article we present a clinical review of current diagnostics and treatment, as well as the challenges and opportunities inherent in developing improved and more personalised treatment.
Insights
Glioblastoma, a severe brain cancer, lacks major treatment advances despite molecular progress. This review covers current diagnostics, treatments, and future opportunities for personalized therapies.
Area of Science:
- Neuro-oncology
- Cancer biology
- Clinical medicine
