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Electrochemical biosensor detection on respiratory and flaviviruses
Phaik Ching Ang1, Veeradasan Perumal2,3, Mohamad Nasir Mohamad Ibrahim1
1School of Chemical Sciences, Universiti Sains Malaysia, 11800, Gelugor, Penang, Malaysia.
Applied Microbiology and Biotechnology
|January 31, 2023
Summary
Electrochemical biosensors offer a rapid and sensitive method for detecting respiratory viruses and flaviviruses. This technology addresses limitations of traditional methods, enabling faster point-of-care diagnostics for public health.
Area of Science:
- * Biomedical Engineering
- * Analytical Chemistry
- * Infectious Disease Diagnostics
Background:
- * Global spread of viruses like respiratory viruses and flaviviruses poses significant public health challenges.
- * Conventional diagnostic methods, such as polymerase chain reaction (PCR), are often time-consuming and require sample purification.
- * There is an urgent need for rapid, portable, and sensitive diagnostic tools for early-stage viral infection detection.
Purpose of the Study:
- * To review the recent advancements in electrochemical sensors for detecting respiratory viruses and flaviviruses.
- * To highlight the potential of electrochemical biosensors as point-of-care (POC) diagnostic technologies.
- * To discuss future trends and perspectives in rapid viral detection sensors.
Main Methods:
- * Comprehensive review of literature on electrochemical sensors for virus detection over the last decade.
- * Analysis of sensor performance, including sensitivity, selectivity, and speed.
- * Discussion of the advantages of electrochemical methods over conventional techniques.
Main Results:
- * Electrochemical sensors demonstrate high performance in detecting specific viruses with enhanced sensitivity and selectivity.
- * These sensors can overcome limitations associated with traditional diagnostic methods.
- * The review covers developments in detecting both respiratory viruses and flaviviruses.
Conclusions:
- * Electrochemical biosensors are a promising technology for rapid and accurate viral detection.
- * They offer a viable solution for point-of-care diagnostics, improving clinical analysis and public health response.
- * Further research into future perspectives will drive innovation in rapid clinical detection sensors for viruses.

