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Updated: Aug 12, 2025

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Surgical Management of Congenital Lung Malformations
Alice King1,2,3, Oluyinka O Olutoye1, Timothy C Lee1,2,3
1Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
Abstract:
Congenital lung malformations (CLMs) are commonly diagnosed prenatal lesions with varied natural history. Prenatal diagnosis and monitoring help to guide fetal interventions, delivery planning, and need for urgent perinatal surgical interventions. All prenatally diagnosed CLMs should be evaluated postnatally, typically with cross-sectional imaging, because many lesions persist despite the appearance of complete 'regression' in utero. Management of CLMs in asymptomatic infants weighs the surgical and anesthetic risk of prophylactic resection against the risk of expectant management, including the possibility of infection, malignant degeneration, and more complicated surgical resection later with loss of compensatory lung growth.
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