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Updated: Aug 12, 2025

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
Published on: September 29, 2020
Capnography for catheter location confirmation in minimally invasive surfactant administration
Itamar Nitzan1,2, Rawan Abu Omar3,4, Francis B Mimouni3,5
1Shaare Zedek Medical Center, Jerusalem, Israel. itamarnitzan@gmail.com.
Objectives:
Minimally Invasive Surfactant Treatment (MIST) is a common method for administering surfactant as a treatment for respiratory distress syndrome. However, tracheal catheter placement can be difficult to confirm. We assessed the presence of carbon dioxide (CO2) in tracheal and esophageal gas aspirated using CO2 detector.
Study Design:
Retrospective arm: 20 infants, MIST catheter placement was assessed with a CO2 detector in two techniques and confirmed with clinical response. Prospective arm-10 infants, aimed to check for CO2 presence in aspirated esophageal gas during routine nasogastric tube insertion.
Results:
Retrospective arm: All infants had positive capnography. One infant that had no clinical response to MIST was diagnosed with total anomalous pulmonary venous return. All 10 infants of the prospective arm had a Negative capnography (P < 0.001, Fisher's exact test).
Conclusions:
Readily available CO2 detectors can distinguish between tracheal and esophageal placement of MIST catheters prior to MIST.
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