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Infantile Tremor Syndrome With Movement Disorder: Current Perspective.

Sudesh Kumar1, Surendra Sah1, Prajna Ray1

  • 1Pediatrics, Mata Gujri Memorial Medical College, Kishanganj, IND.

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|February 1, 2023
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Summary
This summary is machine-generated.

Infantile tremor syndrome, linked to exclusive breastfeeding and poor complementary feeding, can cause severe developmental delays. Early diagnosis and vitamin B12 treatment are crucial for recovery.

Keywords:
breastfedmacrocytic anemiapallortremorvitamin b12 deficiency

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Area of Science:

  • Pediatrics
  • Neurology
  • Nutritional Science

Background:

  • Infantile tremor syndrome (ITS) is a rare neurological disorder.
  • ITS is often associated with nutritional deficiencies in infants.
  • Exclusive breastfeeding without adequate complementary feeding is a potential risk factor.

Observation:

  • A 9-month-old infant exclusively breastfed presented with irritability, listlessness, grade 2 malnutrition, tremors, hyperpigmentation, scarce scalp hair, and developmental delays.
  • Laboratory results showed macrocytic anemia and low vitamin B12 levels (205 pg/dL).
  • MRI revealed cerebral and mild cerebellar atrophy.

Findings:

  • The patient was diagnosed with infantile tremor syndrome.
  • Treatment with vitamin B12 supplementation, along with zinc, magnesium, folic acid, and iron, led to significant improvement.
  • The infant's tremors resolved, and responsiveness and interest in surroundings increased.

Implications:

  • Early recognition and prompt treatment of infantile tremor syndrome are essential.
  • Promoting proper infant nutrition, timely complementary feeding, and appropriate weaning practices can help prevent ITS.
  • This case highlights the critical role of nutrition in infant neurodevelopment.