Related Experiment Video For dermatology
Updated: Aug 12, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Incipient Melanonychia: Benign Finding or Occult Malignancy? A Case Report of Subungual Melanoma
Alejandro J Quiroz Alfaro1, Juliana Greiffenstein2, Andrés Felipe Herrera Ortiz3,4
1Medicine and Health Sciences, Universidad Colegio Mayor de Nuestra Señora del Rosario, Bogotá D.C., COL.
Abstract:
Subungual melanomas are rare neoplasms that tend to debut as longitudinal melanonychia. They are primarily found in patients over 60 years of age and are usually diagnosed late, representing a diagnostic challenge. We present a case report of a 59-year-old female Hispanic patient who initially presented with melanonychia and was eventually diagnosed with subungual melanoma in situ. She was surgically treated and, after three months, remained healthy. Relevant risk factors, clinical and onychoscopic findings, diagnostic criteria, and treatment options are also discussed. Since many benign entities present similarly, high clinical suspicion is critical for diagnosing this entity.
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