Pediatric Stroke in the Southern Region of Iran: A Retrospective Prognostic Cohort Study
Related Experiment Video
Updated: Aug 12, 2025
Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Hamid Nemati1, Leila Behrad2, Hossein Esmaeil Zadeh2
1Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Insights
Childhood stroke, both ischemic and hemorrhagic, frequently leads to long-term impairments. This study in Iran found that most children experienced poor or severe outcomes, highlighting the need for better management strategies.
Area of Science:
- Pediatric Neurology
- Neuroscience
- Public Health
Background:
- Childhood stroke significantly impacts survivors' long-term development and quality of life.
- Effective management and understanding of neurological outcomes are crucial for pediatric stroke patients.
Purpose of the Study:
- To evaluate the neurological developmental outcomes of children with ischemic and hemorrhagic stroke.
- To analyze stroke characteristics and common symptoms in a pediatric cohort.
- To assess outcomes over a five-year follow-up period.
Main Methods:
- Retrospective cohort study of children admitted for stroke between 2012-2015.
- Data collected via medical record review and clinical follow-up visits.
- Statistical analysis performed using SPSS 21.0.
Main Results:
- Hemorrhagic stroke (53.1%) was more common than ischemic stroke (46.9%) in children.
- Decreased level of consciousness (40.6%) and headaches (37.5%) were the most frequent presenting symptoms.
- A significant majority of patients (73.3% ischemic, 52.9% hemorrhagic) had poor or severe outcomes.
Conclusions:
- Hemorrhagic stroke and trauma were identified as common causes in this pediatric population.
- The left sensorimotor area was frequently affected in both stroke types.
- The high rate of poor outcomes underscores the severity of childhood stroke and the need for intervention.
Objective:
Childhood stroke is linked to high personal costs for affected children and their families since more than half of the survivors are impaired for a long time, hampering their normal development and lifestyle. Thus, the present study aimed to evaluate the neurological developmental outcomes of children admitted to Namazi hospital, Shiraz, Iran, for ischemic and hemorrhagic stroke with a five-year follow-up. Ma a retrospective cohort study on children admitted to Namazi Hospital due to ischemic and hemorrhagic stroke during the past three years (2012-2015). The information was collected by reviewing the medical records and clinically visiting the patients on follow-up. The SPSS 21.0 software was used for statistical analysis.
Materials & Method:
This is a retrospective cohort study on children admitted to Namazi hospital due to ischemic and hemorrhagic stroke during past three years (2012-2015). The information was collected by reviewing the medical records and clinically visiting the patients at the time of follow up. The SPSS 21.0 software was used for statistical analysis Settings.
Results:
The patients' mean age at the time of stroke was 6.87 ± 4.60 years. The mean follow-up period was 3.5 ± 1.64 years. 53.1% of the children (N=17) were diagnosed with hemorrhagic stroke, and 46.9% (N=15) with ischemic stroke. The most frequent symptoms first presented by the study population were a decrease in the level of consciousness (LOC) (40.6%), headaches (37.5 %), and hand/arm/leg weakness (34.4%), respectively. The number of patients in the poor.and severe outcome group was 73.3% in the ischemic and 52.9% in the hemorrhagic group.
Conclusion:
Hemorrhagic stroke was slightly more frequent than ischemic stroke, and stroke was more frequent in boys. A decrease in LOC and headaches were the most common symptoms upon admission. The left sensorimotor area was the most involved in both ischemic and hemorrhagic groups. In addition, trauma was the most common cause of stroke in this study population.
