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Structural and Functional Neural Alterations in Internet Addiction: A Study Protocol for Systematic Review and
Jun-Li Liu1, Jing-Ting Sun2,3, Hui-Lin Hu4
1Xi'an Technological University, Xi'an, China.
Psychiatry Investigation
|February 1, 2023
Summary
This meta-analysis examines brain changes in internet addiction (IA). It synthesizes voxel-based morphometry and resting-state functional connectivity studies to clarify IA
Area of Science:
- Neuroimaging
- Psychiatry
- Computational Neuroscience
Background:
- Neuroimaging studies indicate structural and functional brain alterations in individuals with internet addiction (IA).
- Existing research presents conflicting conclusions regarding the specific brain changes associated with IA.
- A consolidated understanding is needed to guide future research and clinical interventions for IA.
Purpose of the Study:
- To conduct a systematic review and meta-analysis of voxel-based morphometry (VBM) and resting-state functional connectivity (rsFC) studies in IA.
- To reach a consolidated conclusion on the neurobiological impact of IA.
- To identify future research directions in the field of IA neuroimaging.
Main Methods:
- Comprehensive literature search of PubMed, Cochrane Library, and Web of Science databases for IA studies (VBM and rsFC) up to August 2021.
- Systematic review and, if data permits, meta-analysis using activation likelihood estimation (ALE) and seed-based d mapping (SDM).
- Analysis of both structural (VBM) and functional (rsFC) brain alterations in IA patients.
Main Results:
- This section will present the synthesized findings from the meta-analysis, detailing consistent structural and functional brain alterations observed in IA.
- Specific brain regions and networks showing significant changes will be identified.
- The results will highlight areas of convergence and divergence across existing studies.
Conclusions:
- The study aims to provide a consolidated conclusion on the neurobiological underpinnings of internet addiction (IA).
- Findings will clarify the impact of IA on brain structure and function.
- This work will offer insights for future research and potential therapeutic strategies for IA.
Keywords:
Internet addictionResting state functional connectivitySmartphoneSocial mediaVoxel-based morphometryMore Related Videos
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