Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Blood-brain Barrier

The Blood-brain Barrier

Special Features of Adaptive Immunity

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...

Cell-mediated Immune Responses

Cell-mediated Immune Responses

What is the Immune System?

What is the Immune System?

Introduction to Innate and Adaptive Immunity

Introduction to Innate and Adaptive Immunity

The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...

Immunological Memory

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CXCL16-mediated recruitment of γδ T cells to the brain reduces sociability in mice.

Science immunology·2026

Same author

Senescence of T cells and organ aging.

Inflammation and regeneration·2026

Same author

Evaluation of an educational program for nurses on the care coordination of pleural mesothelioma patients: A pilot randomized controlled trial.

Japan journal of nursing science : JJNS·2026

Same author

M cell-dependent commensal uptake confers encephalitogenic phenotypes on γδT17 cells in Peyer's patches.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Stage-specific roles of clonally expanded CD8<sup>+</sup> T cells in regulating amyloid pathology in Alzheimer's disease models.

Nature communications·2025

Same author

The astrocytic ensemble acts as a multiday trace to stabilize memory.

Nature·2025

Search research articles

Related Experiment Video

Updated: Aug 12, 2025

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia

Published on: July 26, 2024

Immunity in the brain and surrounding tissues.

Mitsuhiro Kanamori¹, Minako Ito¹

¹Division of Allergy and Immunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Journal of Biochemistry

|February 1, 2023

Summary

This summary is machine-generated.

The brain

Keywords:

brain cerebrospinal fluid meninges

More Related Videos

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

Published on: February 3, 2022

Related Experiment Videos

Last Updated: Aug 12, 2025

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia

Published on: July 26, 2024

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

Published on: February 3, 2022

Area of Science:

Neuroimmunology
Immunology
Cell Biology

Background:

The brain's immune reactions require strict regulation.
Neuroimmunology research has revealed immune cell activity within the brain and adjacent tissues.
Various immune cells and stromal cells are present in border tissues, even during normal physiological conditions.

Conclusions:

Understanding neuroimmune interactions is crucial for comprehending brain function and disease.
Stromal cells may have important, yet underappreciated, roles in supporting immune reactions in the brain.
Further research into adaptive immunity and stromal cell functions can offer new therapeutic targets.